1382748-80-2

Basic information

• Product Name: C₁₂H₁₃N₃O₂
• Synonyms: C₁₂H₁₃N₃O₂
• CAS NO: 1382748-80-2
• Molecular Weight: 231.254
• Mol File: 1382748-80-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₃N₃O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₃N₃O₂(1382748-80-2)
• EPA Substance Registry System: C₁₂H₁₃N₃O₂(1382748-80-2)

Safety Data

• Hazardous Substances Data: 1382748-80-2(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 16312-86-0 4-benzyl-1,2,4-triazolidine-3,5-dione 
• 109-64-8 1,3-dibromo-propane 
• 82514-35-0 C₂₁H₁₇NO₄ 

Relevant articles and documents

An efficient and general urazole synthesis

A general two-step scheme for the synthesis of N4 substituted urazoles (i.e., 1,2,4-triazolin-3,5-diones) is described. The first step involves the reaction of a primary amine with 2.5 equiv of phenyl chloroformate to produce diphenyl (N-substituted)imidodicarbonates. The second step involves the reaction of these compounds with hydrazine to produce N4 substituted urazoles. The mild reaction conditions permit synthesis of N4 oxygenated urazoles, not available via existing methodology. Bicyclic urazoles can be prepared through the subsequent reaction of these N4-protected urazoles with 2.5 equiv of NaH in DMF together with either 1,3-dibromopropane or 2-(tert-butyldimethylsilyloxy)-1,3- dibromopropane in the presence of NaI. The resultant bicyclic urazoles are observed to display varying degrees of pyrimidalization at N1 and N2, depending on substituents.