1383470-42-5

Basic information

• Product Name: C₁₁H₁₁BrN₂
• CAS NO: 1383470-42-5
• Molecular Weight: 251.126
• Mol File: 1383470-42-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₁H₁₁BrN₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₁H₁₁BrN₂(1383470-42-5)
• EPA Substance Registry System: C₁₁H₁₁BrN₂(1383470-42-5)

Safety Data

• Hazardous Substances Data: 1383470-42-5(Hazardous Substances Data)

Upstream product

• 4812-23-1 2-nitro-but-2-ene 
• 158918-49-1 N’-(2-bromobenzylidene)-4-methylbenzenesulfonohydrazide 

Relevant articles and documents

Synthesis of Pyrazolo[5,1-a]isoquinolines and 8-Methylenepyrazolo[5,1-a]isoindoles via Regioselective C-C Coupling and Alkyne Hydroamination

An efficient and convenient synthesis of pyrazolo[5,1-a]isoquinolines has been achieved via palladium-catalyzed Sonogashira coupling of terminal alkynes with 5-(2-bromophenyl)-1H-pyrazoles, in situ formed from the condensation of 1-(2-bromophenyl)buta-2,3-dien-1-ones with hydrazine hydrate, followed by 6-endo intramolecular alkyne hydroamination. More interestingly, 8-methylenepyrazolo[5,1-a]isoindoles, the regioisomer of pyrazolo[5,1-a]isoquinolines, could also be selectively synthesized from the same starting materials through an initial intermolecular hydroamination of terminal alkynes with 5-(2-bromophenyl)-1H-pyrazoles followed by a palladium-catalyzed 5-exo intramolecular Heck coupling reaction.