1383484-01-2Relevant articles and documents
Nickel catalyzed alkylation of N-aromatic heterocycles with Grignard reagents through direct C-H bond functionalization
Xin, Peng-Yang,Niu, Hong-Ying,Qu, Gui-Rong,Ding, Rui-Fang,Guo, Hai-Ming
, p. 6717 - 6719 (2012)
A novel protocol for nickel-catalyzed direct sp2 C-H bond alkylation of N-aromatic heterocycles has been developed. This new reaction proceeded efficiently at room temperature using a Grignard reagent as the coupling partner. This approach prov