1383628-27-0Relevant articles and documents
Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity
Suchaud, Virginie,Bailly, Fabrice,Lion, Cedric,Tramontano, Enzo,Esposito, Francesca,Corona, Angela,Christ, Frauke,Debyser, Zeger,Cotelle, Philippe
, p. 3988 - 3992 (2012/07/03)
We report herein the synthesis of a series of 3-hydroxyquinolin-2(1H)-one derivatives. Esters and amide groups were introduced at position 4 of the basis scaffold and some modulations of the benzenic moiety were performed. Most compounds presented selecti