138371-99-0Relevant articles and documents
Preparation method of pyrrole derivative and intermediate thereof
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Paragraph 0233-0235, (2021/10/27)
The invention discloses a preparation method of a pyrrole derivative and an intermediate thereof. , 2, 4 -dichlorophenol and 4 -bromo - 1H - pyrrole -2 - formaldehyde which are wide in source are used as raw materials and are substituted. The target compo
Directed lithiation of N -benzenesulfonyl-3-bromopyrrole. Electrophile-controlled regioselective functionalization via dynamic equilibrium between C-2 and C-5 lithio species
Fukuda, Tsutomu,Ohta, Takeshi,Sudo, Ei-Ichi,Iwao, Masatomo
supporting information; experimental part, p. 2734 - 2737 (2010/08/19)
(Figure presented) Directed lithiation of N-benzenesulfonyl-3-bromopyrrole (1) with LDA in THF at -78 °C generated C-2 lithio species 3 selectively. Reactions of 3 with reactive electrophiles produced the corresponding 2-functionalized pyrroles 4. On the
The Second Generation Synthesis of a Tumor Promoter Pendolmycin
Okabe, Kazuaki,Natsume, Mitsutaka
, p. 7615 - 7624 (2007/10/02)
Total synthesis of a tumor promoter pendolmycin (1) was accomplished in the stereospecific manner using a D-serine derivative 7 and an L-valine derivative 16 as chiral sources.Methyl 2-(bromomethyl)benzoate was used for the critical step of the indole cyc