138373-91-8

Basic information

• Product Name: 1-azido-1-phenyl-2-(N-tert-butoxycarbonylamino)ethane
• Synonyms: 1-azido-1-phenyl-2-(N-tert-butoxycarbonylamino)ethane
• CAS NO: 138373-91-8
• Molecular Weight: 262.312
• Mol File: 138373-91-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-azido-1-phenyl-2-(N-tert-butoxycarbonylamino)ethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-azido-1-phenyl-2-(N-tert-butoxycarbonylamino)ethane(138373-91-8)
• EPA Substance Registry System: 1-azido-1-phenyl-2-(N-tert-butoxycarbonylamino)ethane(138373-91-8)

Safety Data

• Hazardous Substances Data: 138373-91-8(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 24424-99-5 di-tert-butyl dicarbonate 
• 22710-73-2 1,2-diazido-1-phenylethane 
• 7568-93-6 2-Amino-1-phenylethanol 
• 67341-07-5 tert-butyl N-(2-hydroxy-2-phenylethyl)carbamate 

Relevant articles and documents

Photoredox Catalytic Three-Component Amidoazidation of 1,3-Dienes

In spite of the obvious synthetic potential of functionalized allylic azides, only limited synthetic routes have been developed. We report herein a three-component 1,2-amidoazidation of 1,3-dienes. In the presence offac-Ir(ppy)3under blue LED irradiation, reaction of 1-aryl substituted 1,3-dienes withN-amidopyridinium salt and trimethylsilyl azide (TMSN3) affords exclusively the 1,2-amidoazidation products. The 1-alkyl substituted counterparts undergo the same reaction with moderate to high 1,2- vs 1,4-selectivity. Reduction of this mixture with PPh3under dynamic kinetic conditions enriches significantly one of the two isomers thanks to the facile 1,3-azide shift (Winstein rearrangement) of the allyl azides.

SYNTHESIS OF 1,2-AMINOAZIDES. CONVERSION TO UNSYMMETRICAL VICINAL DIAMINES BY CATALYTIC HYDROGENATION OR REDUCTIVE ALKYLATION WITH DICHLOROBORANES.

1,2-aminoazides are easily prepared from 1,2-amino alcohols.Catalytic hydrogenation in the presence of palladium on charcoal or reductive alkylation with dichloroboranes afford with good yields unsymmetrically substituted vicinal diamines.