1384194-57-3Relevant articles and documents
Photophysical properties of 2,3-dihydroquinazolin-4(1H)-one derivatives
Cabrera-Rivera, Fanny A.,Escalante, Jaime,Morales-Rojas, Hugo,Zigler, David F.,Schmidt, Robert D.,Jarocha, Lauren E.,Forbes, Malcolm D.E.
, p. 31 - 37 (2014/10/15)
2,3-Dihydroquinazolin-4(1H)-one (DHQ) derivatives were synthesized by treatment of isatoic anhydride with amines and subsequent cyclocondensation with aldehydes or ketones. The derivatives were characterized by 1H and 13C NMR, elemental analysis and HRMS. Absorption and emission spectra of DHQ derivatives were recorded in different solvents (hexadecane, benzene, chloroform, methanol and acetonitrile). Both the absorption and the emission maxima are solvent-dependent and red-shifted. Molar extinction coefficients were determined to be 2364-4820 M-1 cm-1. The Stokes shifts of the compounds are large and increase with solvent polarity. This feature and the bathochromic effect shown for the absorption and emission processes indicate that the dipole moment of these fluorescent molecules is higher in the excited state than in the ground state. The fluorescence quantum yield and lifetime were obtained in different solvents for DHQ 4.
Photoinduced elimination in 2,3-dihydro-2-tert -butyl-3-benzyl-4(1 h)-quinazolinone: Theoretical calculations and radical trapping using TEMPO derivatives
Cabrera-Rivera, Fanny Araceli,Ortz-Nava, Claudia,Escalante, Jaime,Hernández-Pérez, Julio M.,H?, Minhhuy
, p. 1057 - 1063 (2012/06/17)
Photochemical irradiation of 2,3-dihydro-2-tert-butyl-3-benzyl-4(1H)- quinazolinone produced 3-benzyl-4(3H)-quinazolinone through photoinduced elimination via a radical mechanism. The use of photochemical conditions such as chloroform and UV irradiation (δ= 254 nm) got the 3-benzyl-4(3H)- quinazolinone in a high yield. Some theoretical calculations were achieved to explain the mechanism and the presence of radical intermediates was confirmed by trapping with different 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) derivatives. Georg Thieme Verlag Stuttgart · New York.