138436-19-8

Basic information

• Product Name: (R)-(E)-2-<<<(p-Methoxybenzyl)oxy>methoxy>methyl>-5-methylhex-3-en-1-ol
• Synonyms: (R)-(E)-2-<<<(p-Methoxybenzyl)oxy>methoxy>methyl>-5-methylhex-3-en-1-ol
• CAS NO: 138436-19-8
• Molecular Weight: 294.391
• Mol File: 138436-19-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-(E)-2-<<<(p-Methoxybenzyl)oxy>methoxy>methyl>-5-methylhex-3-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(E)-2-<<<(p-Methoxybenzyl)oxy>methoxy>methyl>-5-methylhex-3-en-1-ol(138436-19-8)
• EPA Substance Registry System: (R)-(E)-2-<<<(p-Methoxybenzyl)oxy>methoxy>methyl>-5-methylhex-3-en-1-ol(138436-19-8)

Safety Data

• Hazardous Substances Data: 138436-19-8(Hazardous Substances Data)

Upstream product

• 88023-78-3 para-methoxybenzyl chloride 
• 155489-75-1 (2R,3E)-2-(hydroxymethyl)-5-methylhex-3-enyl acetate 
• 133575-94-7 Acetic acid (E)-(S)-2-hydroxymethyl-5-methyl-hex-3-enyl ester 
• 51615-30-6 diethyl 2-(3-methylbutylidene)malonate 
• 138435-98-0 diethyl (E)-2-(3-methyl-1-butene-1-yl)malonate 
• 138436-01-8 (E)-2-(3-methyl-1-buten-1-yl)-1,3-propanediol 
• 133490-81-0 (E)-1-Acetoxy-2-(acetoxymethyl)-5-methyl-3-hexene 
• 590-86-3 isovaleraldehyde 

Downstream Products

• 138436-26-7 (S)-(E)-1-<(tert-Butyldiphenylsilyl)oxy>-2-<<<(p-methoxybenzyl)oxy>methoxy>methyl>-5-methylhex-3-ene 
• 138436-31-4 (S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxymethoxymethyl)-propionaldehyde 
• 155125-19-2 (2S,3R)-2-[(R)-1-Benzyloxymethoxymethyl-2-(4-methoxy-benzyloxymethoxy)-ethyl]-3-propyl-oxirane 
• 155125-04-5 (S)-1-(4-methoxybenzyloxymethoxy)-2-(triisopropylsilyloxymethyl)-3(Z)-heptene 
• 155125-05-6 (S)-5-(4-methoxybenzyloxymethoxy)-4-(triisopropylsilyloxymethyl)-2(Z)-pentene 
• 152669-40-4 (S)-3-(4-methoxybenzyloxymethoxy)-2-(triisopropylsilyloxymethyl)-1-propanol 
• 138436-32-5 (S)-2-(4-Methoxy-benzyloxymethoxymethyl)-3-triisopropylsilanyloxy-propionaldehyde 
• 138760-95-9 (R)-2-(4-methoxybenzyloxymethoxy)-3(Z)-hepten-1-ol 
• 155125-14-7 (R)-2-(4-methoxybenzyloxymethoxy)-3(Z)-hepten-1-ol 
• 138436-27-8 Triisopropyl-[(E)-(S)-2-(4-methoxy-benzyloxymethoxymethyl)-5-methyl-hex-3-enyloxy]-silane 

Relevant articles and documents

Stereodivergent synthesis of cis epoxides derived from asymmetrized 2-alkenyl-1,3-propanediols

Cis epoxides of any desired absolute stereochemistry have been obtained in a high enantio- and diastereodivergent manner via diastereospecific epoxidation of asymmetrized (Z)-2-alkenyl-1,3-propanediols, in turn obtained through a chemoenzymatic route, and a protection-deprotection 'trick' on hydroxy groups.

Protecting group controlled diastereoselective allylation of asymmetrized bis (hydroxymethyl) acetaldehydes (BHYMA)

MgBr2 catalysed allylation of a series of diprotected asymmetrized bis (Hydroxymethyl) acetaldehydes 2 with allyltributylstannane proceeds with good diastereoselectivity. The stereochemical results are in line with a cyclic chelated transition state, where only one of the two CH2OR appendages, due to the different nature of protecting groups, is capable of coordinating the Lewis acid.