138436-25-6

Basic information

• Product Name: (R)-(E)-1-<(tert-Butyldiphenylsilyl)oxy>-2-<<<(p-methoxybenzyl)oxy>methoxy>methyl>-5-methylhex-3-ene
• Synonyms: (R)-(E)-1-<(tert-Butyldiphenylsilyl)oxy>-2-<<<(p-methoxybenzyl)oxy>methoxy>methyl>-5-methylhex-3-ene
• CAS NO: 138436-25-6
• Molecular Weight: 532.795
• Mol File: 138436-25-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-(E)-1-<(tert-Butyldiphenylsilyl)oxy>-2-<<<(p-methoxybenzyl)oxy>methoxy>methyl>-5-methylhex-3-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(E)-1-<(tert-Butyldiphenylsilyl)oxy>-2-<<<(p-methoxybenzyl)oxy>methoxy>methyl>-5-methylhex-3-ene(138436-25-6)
• EPA Substance Registry System: (R)-(E)-1-<(tert-Butyldiphenylsilyl)oxy>-2-<<<(p-methoxybenzyl)oxy>methoxy>methyl>-5-methylhex-3-ene(138436-25-6)

Safety Data

• Hazardous Substances Data: 138436-25-6(Hazardous Substances Data)

Upstream product

• 88023-78-3 para-methoxybenzyl chloride 
• 138436-20-1 (R)-(E)-2-<<(tert-Butyldiphenylsilyl)oxy>methyl>-5-methylhex-3-en-1-ol 
• 133575-94-7 Acetic acid (E)-(S)-2-hydroxymethyl-5-methyl-hex-3-enyl ester 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 133490-81-0 (E)-1-Acetoxy-2-(acetoxymethyl)-5-methyl-3-hexene 
• 138436-01-8 (E)-2-(3-methyl-1-buten-1-yl)-1,3-propanediol 
• 138435-98-0 diethyl (E)-2-(3-methyl-1-butene-1-yl)malonate 
• 51615-30-6 diethyl 2-(3-methylbutylidene)malonate 
• 590-86-3 isovaleraldehyde 
• 155489-75-1 (2R,3E)-2-(hydroxymethyl)-5-methylhex-3-enyl acetate 

Downstream Products

• 140479-44-3 (2R,3S)-1-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxymethoxymethyl)-hex-5-en-3-ol 
• 140479-40-9 (2R,3R)-1-((tert-butyldiphenylsilyl)oxy)-2-((((p-methoxybenzyl)oxy)methoxy)methyl)hex-5-en-3-ol 
• 140479-54-5 (4R,5R)-trans-4-allyl-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyl-1,3-dioxane 
• 140479-50-1 (2R,3R)-2-(((tert-butyldiphenylsilyl)oxy)methyl)hex-5-ene-1,3-diol 
• 146512-63-2 (4R,5R)-cis-4-allyl-5-((((4-methoxybenzyl)oxy)methoxy)methyl)-2,2-dimethyl-1,3-dioxane 
• 146512-61-0 (2S,3R)-2-((((4-methoxybenzyl)oxy)methoxy)methyl)hex-5-ene-1,3-diol 
• 152669-37-9 (R)-3-<<(t-butyldiphenyl)silyl>oxy>-2-<<<(p-methoxybenzyl)oxy>methoxy>methyl>-1-propanol 
• 138436-30-3 (R)-3-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxymethoxymethyl)-propionaldehyde 

Relevant articles and documents

Chemoenzymatic Preparation of Asymmetrized Tris(hydroxymethyl)methane (THYM*) and of Asymmetrized Bis(hydroxymethyl)acetaldehyde (BHYMA*) as New Highly Versatile Chiral Building Blocks

A series of asymmetrized tris(hydroxymethyl)methanes 2 and bis(hydroxymethyl)acetaldehydes 3 have been prepared in both enantiomeric forms through a chemoenzymatic methodology.The key step is the highly enantioselective PPL-catalyzed monohydrolysis of 2(E)-alkenyl-1,3-diacetoxypropanes 25-27.A careful study on the effect of unsaturations adjacent to the prochiral center in a series of 2-substituted 1,3-diacetoxypropanes has confirmed the suggested beneficial effect of a ? system in that position but has also unveiled an unprecedented dramatic effect of double-bond configuration on enantioselectivity.A new empirical model for the interpretation of these and other results, based both on polarity and steric arguments, is proposed.This study provides a general protocol for the efficient synthesis of asymmetrized 1,3-propanediols bearing in position 2 saturated or unsaturated carbon chains.