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13849-91-7

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13849-91-7 Usage

Description

Pomolic Acid, a pentacyclic triterpene derived from Euscaphis japonica, is an inhibitor of CXCR4. It is known for its anti-cancer and anti-viral properties, making it a potential therapeutic agent for various medical applications.

Uses

Used in Anticancer Applications:
POMOLIC ACID is used as an anticancer agent for its ability to inhibit cancer metastasis. It targets MCF7 human breast cancer cells, demonstrating potential in the treatment of cancer metastasis.
Used in Antiviral Applications:
POMOLIC ACID is used as an anti-viral agent for its effectiveness against HIV, showcasing its potential in combating viral infections.

Check Digit Verification of cas no

The CAS Registry Mumber 13849-91-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,8,4 and 9 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 13849-91:
(7*1)+(6*3)+(5*8)+(4*4)+(3*9)+(2*9)+(1*1)=127
127 % 10 = 7
So 13849-91-7 is a valid CAS Registry Number.
InChI:InChI=1/C30H48O4/c1-18-10-15-30(24(32)33)17-16-27(5)19(23(30)29(18,7)34)8-9-21-26(4)13-12-22(31)25(2,3)20(26)11-14-28(21,27)6/h8,18,20-23,31,34H,9-17H2,1-7H3,(H,32,33)/t18-,20?,21-,22+,23+,26+,27-,28-,29-,30+/m1/s1

13849-91-7Relevant articles and documents

En route to anti-glioblastoma active pomolic acid

Kraft, Oliver,Wiemann, Jana,Al-Harrasi, Ahmed,Csuk, René

, p. 29 - 32 (2019/05/06)

Tormentic acid (3) can be easily photo-reduced by Saito's procedure and is an ideal starting material for the straightforward synthesis of pomolic acid (1).

Triterpenoid saponins from Ilex mamillata C.Y. Wu ex C.J. Tseng

Che, Yan-Yun,Tu, Peng-Fei,Zhang, Liang,Li, Ning,Zeng, Ke-Wu

, p. 1991 - 1995,5 (2020/09/09)

Two new triterpenoid saponins, ilemaminosides A and B (1 and 2) along with six known saponins (3-8) were isolated from 70% ethanolic extract of the leaves of Ilex mamillata C.Y. Wu ex C.J. Tseng. The new saponins were characterised as 3-O -α- L-arabinopyranosyl-ilexgenin B (1) and 3-O-β-D- glucopyranosyl-(1→3) -α-L-arabinopyranosyl-ilexgenin B (2). The structures of compounds 1 and 2 were elucidated on the basis of the chemical and spectroscopic methods, and the structures of known compounds were identified by comparison of their spectroscopic data with those reported in the literature. The compounds showed inhibitory activities in anti-inflammatory assay invitro with IC50 values in the range 25.37-38.33gmL1.

Triterpenoid saponins from Ilex latifolia

Ouyang, Ming-An,Liu, Yu-Qing,Wang, Han-Qing,Yang, Chong-Ren

, p. 2483 - 2486 (2007/10/03)

Three new triterpenoid saponins, latifolosides F, G, H were isolated from the leaves of Ilex latifolia. Their structures were elucidated on the basis of chemical and spectral evidence. Latifoloside F was determined to be 3-O-[α-L-rhamnopyranosyl(1-2)]-[β-D-glucopyranosyl(1-3)-]-α-L- arabinopyranosyl ilexgenin B 28-O-[α-L-rhamnopyranosyl(1-2)]-β-D- glucopyranoside. Latifoloside G was 3-O-[α-L-rhamnopyranosyl(1-2)]-[β-D- glucopyranosyl(1-3)-]-α-L-arabinopyranosyl pomolic acid 28-O-[α-L- rhamnopyranosyl(1-2)]-β-D-glucopyranoside. Latifolioside H(3) was 3-O-[α- L-rhamnopyranosyl(1-2)]-[β-D-glucopyranosyl(1-3)-]-α-L-arabinopyranosyl siaresinolic acid 28-O-[α-L-rhamnopyranosyl(1-2)]-β-D-glucopyranoside.

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