138536-05-7Relevant articles and documents
Trifluoromethylalkenes in cycloaddition reactions
Bonnet-Delpon,Begue,Lequeux,Ourevitch
, p. 59 - 70 (2007/10/02)
CF3-Substituted alkenes have been described to be good partners in Diels-Alder reactions with the Danishefsky's diene and in 1,3-dipolar cycloadditions with nitrones and non-stabilized azomethine ylides. The influence of the CF3-grou
1,3-Dipolar Cycloaddition Between Ethyl Trifluoroacetoacetate and N-(Benzylidene)methylamine N-Oxide
Begue, Jean-Pierre,Bonnet-Delpon, Daniele,Lequeux, Thierry
, p. 2888 - 2889 (2007/10/02)
The 1,3-dipolar cycloaddition between ethyl trifluoroacetoacetate and N-(benzylidene)methylamine N-oxide, performed in boiling toluene, leads regio- and stereo-selectively to an isoxazolidine, while the corresponding ethyl acetoacetate is found to be unreactive under the same conditions.On the other hand, α-trifluoromethylstyrene behaves as α-methylstyrene and affords two diastereoisomeric trifluoromethyl-substituted cycloadducts.