13858-67-8

Basic information

• Product Name: 3-cinnamylidene-pentane-2,4-dione
• Synonyms: 3-cinnamylidene-pentane-2,4-dione
• CAS NO: 13858-67-8
• Molecular Weight: 214.264
• Mol File: 13858-67-8.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: 3-cinnamylidene-pentane-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-cinnamylidene-pentane-2,4-dione(13858-67-8)
• EPA Substance Registry System: 3-cinnamylidene-pentane-2,4-dione(13858-67-8)

Safety Data

• Hazardous Substances Data: 13858-67-8(Hazardous Substances Data)

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 41002-50-0 4-acetoxy-3-penten-2-one 
• 104-55-2 3-phenyl-propenal 
• 123-54-6 acetylacetone 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 

Downstream Products

• 1399383-16-4 dimethyl 6-acetyl-7-methyl-3-phenyloxepine-2,2(3H)-dicarboxylate 
• 1399383-04-0 dimethyl 4-acetyl-5-methyl-3-[(E)-2-phenylethenyl]furan-2,2(3H)-dicarboxylate 
• 1399383-36-8 ethyl 6-acetyl-2,3-dihydro-7-methyl-3-phenyloxepine-2-carboxylate 
• 1399383-27-7 ethyl 4-acetyl-2,3-dihydro-5-methyl-3-[(E)-2-phenylethenyl]furan-2-carboxylate 
• 1257319-42-8 C₂₆H₂₄N₂ 
• 1257319-41-7 C₂₆H₂₂N₄O₄ 
• 1257319-44-0 C₂₈H₂₈N₂O₂ 
• 1257319-43-9 C₂₆H₂₄N₂O₂ 
• 87497-31-2 6-Dimethylamino-3-[(E)-3-phenyl-prop-2-en-(Z)-ylidene]-hexane-2,4-dione; hydrobromide 

Relevant articles and documents

Biological screening and DNA nuclease activity of transition metal complexes of N2O2 type of Knoevenagel condensate Schiff base

A novel tetradentate N2O2 type of Knoevenagel condensate Schiff base, synthesized from 4-amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one (4-aminoantipyrine) and 3-(cinnamyl)-pentane-2,4-dione, forms stable complexes with transition met

Corrigendum to: Enzyme Promiscuity as a Remedy for the Common Problems with Knoevenagel Condensation (Chemistry – A European Journal, (2019), 25, 43, (10156-10164), 10.1002/chem.201901491)

In the published paper, there is a mistake in the labelling of compounds in Figure. A corrected version of that Figure appears below. The authors apologise for the mistake. Figure (Figure presented.) Unsaturated 2,4-pentanediones obtained by enzyme-catalyzed tandem Knoevenagel reaction. Reaction conditions: aldehyde (1 mmol), 4-acetoxy-3-penten-2-one (5 a, R1=R2=R3=Me) (3 mmol), and PPL (100 mg) in tert-butyl alcohol/ 5 % H2O v/v (2 mL) for 72 h at 20 °C, 200 rpm. [a] With vinyl acetate. [b] With ethyl β-styrylcarbonate. [c] With styryl acetate.

Cross-linked polystyrene-TiCl4 complex as a reusable Lewis acid catalyst for solvent-free Knoevenagel condensations of 1,3-dicarbonyl compounds with aldehydes

Cross-linked polystyrene copolymer beads with the average particle size in the range of (50–80 mesh size) were prepared by a new method, characterized and functionalized with titanium tetrachloride to afford the corresponding polystyrene?titanium tetrachloride complex in one step reaction and characterized by FT-IR, UV, TGA, DSC, XRD, SEM, BET. This polymer metal complex (PS/TiCl4) was used as a heterogeneous, recoverable, reusable Lewis acid for solvent-free Knoevenagel condensations of 1,3-diketones with aromatic aldehydes under green and mild conditions. The rate of reactions was found to decrease with an increasing percentage of crosslinking and the mesh size of the copolymer beads. This complex showed good stability and catalytic activity in the Knoevenagel reactions.