138603-21-1

Basic information

• Product Name: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[1-(2-chloroethoxy)ethyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
• CAS NO: 138603-21-1
• Molecular Formula: C43H54ClN4O10P
• Molecular Weight: 853.349
• Mol File: 138603-21-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[1-(2-chloroethoxy)ethyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite](CAS DataBase Reference)
• NIST Chemistry Reference: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[1-(2-chloroethoxy)ethyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite](138603-21-1)
• EPA Substance Registry System: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[1-(2-chloroethoxy)ethyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite](138603-21-1)

Safety Data

• Hazardous Substances Data: 138603-21-1(Hazardous Substances Data)

Upstream product

• 124482-92-4 2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine 
• 138603-19-7 1-{(2R,3R,4R,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3-[1-(2-chloro-ethoxy)-ethoxy]-4-hydroxy-tetrahydro-furan-2-yl}-1H-pyrimidine-2,4-dione 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 69304-38-7 3',5'-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)uridine 
• 213548-63-1 2'-O-[1-(2-chloroethoxy)ethyl]-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)uridine 
• 138231-03-5 2'-O-[1-(2-chloroethoxy)ethyl]uridine 

Downstream Products

• 2415-43-2 uridylyl-3',5'-uridine 

Relevant articles and documents

1-(2-CHLOROETHOXYETHYL GROUP FOR THE PROTECTION OF 2'-HYDROXYL GROUP IN THE SYNTHESIS OF OLIGORIBONUCLEOTIDES

The 1-(2-chloroethoxy)ethyl (Cee) group is completely stable under the acidic condition required to remove the 5'-protecting groups in oligonucleotide synthesis, but can be cleaved under the similar conditions to that of the tetrahydropyranyl (Thp) in the