1386977-58-7

Basic information

• Product Name: N₄-p-bromobenzoylcytidine
• Synonyms: N₄-p-bromobenzoylcytidine
• CAS NO: 1386977-58-7
• Molecular Weight: 426.224
• Mol File: 1386977-58-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N₄-p-bromobenzoylcytidine(CAS DataBase Reference)
• NIST Chemistry Reference: N₄-p-bromobenzoylcytidine(1386977-58-7)
• EPA Substance Registry System: N₄-p-bromobenzoylcytidine(1386977-58-7)

Safety Data

• Hazardous Substances Data: 1386977-58-7(Hazardous Substances Data)

Upstream product

• 586-75-4 4-chlorobenzoyl chloride 
• 65-46-3 CYTIDINE 

Downstream Products

• 1386977-60-1 N₄-p-bromobenzoyl-2',3'-O-isopropylidene-O₂,5'-cyclocytidine 
• 1386977-61-2 N4-p-bromobenzoyl-N2-(3-methoxypropyl)amino-N1-(2',3'-O-isopropylidene-β-D-ribofuranosyl)-2(1H)-pyrimidinamine hydrochloride 
• 1386977-62-3 N4-p-bromobenzoyl-N2-(2-hydroxyethyl)amino-N1-(2',3'-O-isopropylidene-β-D-ribofuranosyl)-2(1H)-pyrimidinamine hydrochloride 
• 1386977-63-4 N4-p-bromobenzoyl-N2-benzylamino-N1-(2',3'-O-isopropylidene-β-D-ribofuranosyl)-2(1H)-pyrimidinamine hydrochloride 
• 1386977-64-5 N4-p-bromobenzoyl-N2-isopropylamino-N1-(2',3'-O-isopropylidene-β-D-ribofuranosyl)-2(1H)-pyrimidinamine hydrochloride 
• 1386977-65-6 N4-p-bromobenzoyl-N2-cyclohexylamino-N1-(2',3'-O-isopropylidene-β-D-ribofuranosyl)-2(1H)-pyrimidinamine hydrochloride 
• 1386977-66-7 N₄-p-bromobenzoyl-2',3'-O-isopropylidene-Boc-tBu-lysidine hydrochloride 
• 1386977-67-8 N₄-p-bromobenzoyl-2',3'-O-isopropylidene-diBoc-agmatidine hydrochloride 
• 1386977-59-8 N₄-p-bromobenzoyl-2',3'-isopropylidenecytidine 

Relevant articles and documents

Efficient preparation of 2,4-diaminopyrimidine nucleosides: Total synthesis of lysidine and agmatidine

An efficient route for the synthesis of 2,4-diaminopyrimidine ribosides from cytidine is described consisting of six steps with overall yields >50% and only one chromatographic step. The key amine addition step utilizes LiCl and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) to ensure clean conversion to a single tautomeric product. This route has been used to prepare the modified tRNA nucleosides lysidine and agmatidine in quantities suitable for structural characterization.