138704-14-0 Usage
Description
Cocaine (N-Methyl-d3) is a deuterated analog of cocaine, which is a naturally occurring stimulant drug derived from the coca plant. It is a white to off-white solid and is commonly used in research and forensic applications due to its unique properties. The presence of deuterium (d3) in its molecular structure distinguishes it from the regular cocaine, making it a valuable tool for studying the mechanisms of action and detection of the drug.
Uses
Used in Research Applications:
Cocaine (N-Methyl-d3) is used as a research compound for studying the effects of cocaine on the central nervous system. Its application in this field is crucial for understanding the interactions between cocaine and various neurotransmitter transporters, such as dopamine, norepinephrine, and serotonin. The deuterated analog helps researchers differentiate between the native and administered forms of the drug, providing valuable insights into its pharmacological properties.
Used in Forensic Analysis:
Cocaine (N-Methyl-d3) is used as an internal standard in forensic analysis for the detection and quantification of cocaine in biological samples. Its stable isotopic composition allows for accurate measurements and helps to overcome potential interferences that may arise during the analysis. This application is essential for criminal investigations and legal proceedings, ensuring the reliability of evidence related to cocaine use.
Used in Controlled Substance Monitoring:
As a controlled substance, cocaine is subject to strict regulations and monitoring. Cocaine (N-Methyl-d3) is used in this context to help enforce these regulations and monitor the distribution and use of the drug. Its unique properties make it an effective tool for tracking and identifying the presence of cocaine in various settings, including pharmaceutical, medical, and law enforcement applications.
Used in Anesthetic Applications:
Cocaine (N-Methyl-d3) is used as a local anesthetic in certain medical procedures. Its ability to inhibit the reuptake of neurotransmitters like dopamine, norepinephrine, and serotonin contributes to its numbing effect on nerve endings. This application is particularly useful in minor surgical procedures and dental treatments, where a localized and temporary loss of sensation is required.
Check Digit Verification of cas no
The CAS Registry Mumber 138704-14-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,7,0 and 4 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 138704-14:
(8*1)+(7*3)+(6*8)+(5*7)+(4*0)+(3*4)+(2*1)+(1*4)=130
130 % 10 = 0
So 138704-14-0 is a valid CAS Registry Number.
138704-14-0Relevant articles and documents
Synthesis of N-methyl-trideuterium-labelled m-hydroxybenzoylecgonine as an internal standard for GC/MS analysis
Feng, Shixia,ElSohly, Mahmoud A.
, p. 1031 - 1037 (1999)
m-Hydroxybenzoylecgonine is an important metabolite of cocaine. A synthesis of [8-C2H3]-m-hydroxybenzoylecgonine (7) for use as an internal standard in GC/MS analysis of m-hydroxybenzoylecgonine, is described. N-Demethylation of coca
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