138723-90-7

Basic information

• Product Name: 2,2-Dimethoxy-5,5-dimethyl-
• Synonyms: 2,2-Dimethoxy-5,5-dimethyl-
• CAS NO: 138723-90-7
• Molecular Formula: C₆H₁₂N₂O₃
• Molecular Weight: 160.17108
• Mol File: 138723-90-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 171.2±40.0 °C(Predicted)
• Appearance: /
• Density: 1.17±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2,2-Dimethoxy-5,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-Dimethoxy-5,5-dimethyl-(138723-90-7)
• EPA Substance Registry System: 2,2-Dimethoxy-5,5-dimethyl-(138723-90-7)

Safety Data

• Hazardous Substances Data: 138723-90-7(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 21732-11-6 methyl-2,3-diaza-4-methyl-4-acetoxypent-2-enoate 
• 154027-24-4 2-acetoxy-2-methoxy-5,5-dimethyl-Δ³-1,3,4-oxadiazoline 

Downstream Products

• 43109-63-3 5,5-dimethoxy-1,3-diphenyl-2,4-imidazolidinedione 
• 1069-12-1 1,1,2,2-tetramethoxyethylene 
• 67-64-1 acetone 
• 81505-19-3 dimethyl phenyl orthoformate 
• 185304-90-9 1-Dimethoxymethyl-3,3-dimethoxy-1,3,3a,4,5,6-hexahydro-indol-2-one 
• 146464-79-1 ester methylique de l'acide methoxy-9 fluorene-9 carboxylique 
• 1216-44-0 methyl 9-hydroxy-9H-fluorene-9-carboxylate 
• 201157-00-8 pentafluorobenzoylfluoride dimethyl acetal 
• 18959-17-6 2,4-dinitro-benzoic acid methyl ester 
• 392-56-3 Hexafluorobenzene 
• 553-90-2 Dimethyl oxalate 
• 118-74-1 hexachlorobenzene 
• 51877-62-4 Pentachlorbenzoesaeure-methylester 
• 1825-23-6 pentachlorobenzoyl chloride 

Relevant articles and documents

Reaction of dimethoxycarbene with strained cyclic carbonyl compounds

A cyclopropanone, a cyclopropenone, cyclobutanones, a cyclobutane-1,3-dione, and a cyclobutene-1,2-dione reacted with dimethoxycarbene to afford acetals of the next larger ring by formal insertion of the carbene into a C-C bond α to the carbonyl group. When either of two saturated α-ring carbons could be involved in the process, the ring expansion was selective, affording primarily the product of apparent insertion into the more substituted ring bond. With 2,3-dimethoxycyclobutene-1,2-dione, insertion occurred between the carbonyl groups and with β-propiolactone it occurred at the lactone bond. β-Propiolactam, however, reacted by insertion of the carbene into the N-H bond.

Carbon-Oxygen Bond Insertion in the Reaction of Dialkoxycarbenes with Anhydrides

Dimethoxycarbene (1a) and methoxy(2,2,2-trifluoroethoxy)carbene (1b) were generated in benzene solution by thermolysis of the corresponding 2,2-dialkoxyoxadiazolines 7.The carbenes were trapped by intermolecular reaction with a variety of cyclic anhydrides 8.The products 9 are formally the result of carbene insertion into the bond between the carbonyl carbon and the ring oxygen atoms.The results of a competition between dimethylmaleic and dichloromaleic anhydrides for dimethoxycarbene suggests that this reaction proceeds by nucleophilic attack of dialkoxycarbene onto the carbonyl carbon atom of the anhydride. - Keywords: Carbenes, dialkoxy-; Oxadiazolines; C-O insertion; Carbonyl additions; Anhydrides

Electrooxidative Cyclization of N-Acylhydrazones of Aldehydes and Ketones to Δ3-1,3,4-Oxadiazolines and 1,3,4-Oxadiazoles

The electrolytic oxidation of ketone N-acylhydrazones (1) in methanolic sodium acetate induced their intramolecular cyclization to the corresponding 2-methoxy-Δ3-1,3,4-oxadiazolines 3.The thermal stability of a given oxadiazoline and what products were formed by its thermal decomposition was found to depend on the natures of the substituents at C-2.Thus, 2-methoxy-2-phenyloxadiazolines preferentially yielded oxiranes 5, whereas 2-alkyl-2-methoxyoxadiazolines preferentially gave enol ethers 6. 2,2-Dimethoxyoxadiazolines decomposed to the parent ketones and many unidentified products.The electrolytic oxidation of aldehyde N-acylhydrazones 2 gave 2,5-disubstituted 1,3,4-oxadiazoles 4.The oxidative cyclization of the N-benzoylhydrazones of aliphatic aldehydes gave especially high yields of the corresponding heterocycles.