138813-24-8

Basic information

• Product Name: 4H,9H-Dipyrazolo[1,5-a:1,5-d]pyrazine-4,9-dione(9CI)
• Synonyms: 4H,9H-Dipyrazolo[1,5-a:1,5-d]pyrazine-4,9-dione(9CI);4H,9H-DIPYRAZOLO[1,5-A:1'',5''-D]PYRAZINE-4,9-DIONE
• CAS NO: 138813-24-8
• Molecular Formula: C₈H₄N₄O₂
• Molecular Weight: 0
• Product Categories: PIPERIDINE
• Mol File: 138813-24-8.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4H,9H-Dipyrazolo[1,5-a:1,5-d]pyrazine-4,9-dione(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4H,9H-Dipyrazolo[1,5-a:1,5-d]pyrazine-4,9-dione(9CI)(138813-24-8)
• EPA Substance Registry System: 4H,9H-Dipyrazolo[1,5-a:1,5-d]pyrazine-4,9-dione(9CI)(138813-24-8)

Safety Data

• Hazardous Substances Data: 138813-24-8(Hazardous Substances Data)

Upstream product

• 1621-91-6 1H-pyrazole-3-carboxylic acid 
• 610-14-0 2-nitrobenzyl chloride 
• 7719-09-7 thionyl chloride 
• 855643-75-3 pyrazole carboxylic acid 

Downstream Products

• 138785-61-2 (-)-3(5)-Pyrazolcarboxy<2-(methoxymethyl)pyrrolidid> 
• 138785-59-8 (-)-N-Methyl-N-(1-phenylethyl)-3⁽⁵⁾-pyrazolcarboxamid 
• 138785-60-1 (+)-N-(1-Cyclohexylethyl)-N-methyl-3⁽⁵⁾-pyrazolcarboxamid 
• 1621-91-6 1H-pyrazole-3-carboxylic acid 
• 763108-03-8 1H-pyrazole-3-carboxylic acid methylphenylamide 
• 763107-52-4 2-[(1H-pyrazole-3-carbonyl)amino]thiophene-3-carboxylic acid methyl ester 
• 305346-22-9 N-(3,4-dichlorophenyl)-1H-pyrazole-3-carboxamide 
• 763107-94-4 1H-pyrazole-3-carboxylic acid (2-chlorophenyl)methylamide 
• 305346-17-2 morpholino(1H-pyrazol-3-yl)methanone 

Relevant articles and documents

Hydrotris[3-(carboxypyrrolidido)pyrazol-l-yl]borate, the first proven N3O3-hexadentate homoscorpionate ligand

The new homoscorpionate ligand, hydrotris[3-(carboxypyrrolidido)pyrazol-l-yl]borate, [Tpcpd]-, was synthesized, and it formed with lanthanide(m) ions La, Nd and Sm, structurally characterized [M(Tpcpd)JPF6 complexes, where the lanthanide ion was in a ten-coordinate enviroment consisting of one N3O3 hexadentate Tpcpd ligand, and one N2O2 tetradentate Tpcpd ligand. The Royal Society of Chemistry 2000.

NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF CYSTIC FIBROSIS

The present invention discloses compounds according to Formula I: wherein R1 is as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment cystic fibrosis by administering a compound of the invention.

N-Substituted pyrazole-3-carboxamides as inhibitors of human 15-lipoxygenase

High-throughput screening was used to find selective inhibitors of human 15-lipoxygenase-1 (15-LOX-1). One hit, a 1-benzoyl substituted pyrazole-3-carboxanilide (1a), was used as a starting point in a program to develop potent and selective 15-LOX-1 inhibitors.