1388155-40-5Relevant articles and documents
Three-component domino reaction in PPG: An easy access to 4-thiazolidinone derivatives
Prasad, Davinder,Nath, Mahendra
experimental part, p. 628 - 633 (2012/08/27)
A simple, economical, and convenient synthesis of a new series of 4-thiazolidinone derivatives using one-pot three-component condensation of aromatic amines, thioglycolic acid and aromatic aldehydes or cyclohexanone in polypropylene glycol (PPG), a recyclable and inexpensive solvent medium is reported. All the reactions are carried out at 110°C without using catalyst or additives. The products are obtained in good to excellent yields (60-97%) after easy workup and purification.