1388625-48-6Relevant articles and documents
Copper(II)-mediated dehydrogenative cross-coupling of heteroarenes
Mao, Zhifeng,Wang, Zhe,Xu, Zhaoqing,Huang, Fei,Yu, Zhengkun,Wang, Rui
supporting information; experimental part, p. 3854 - 3857 (2012/09/11)
Cu(OAc)2-mediated dehydrogenative cross-coupling between two heteroarenes has been realized in the absence of any other additive. A mechanism involving a formal Cu(II) to Cu(0) route by convergent disproportionation of the copper mediator is proposed and has been evidenced by copper mirror formation during the reaction. This synthetic protocol provides a concise and "green" access to unsymmetrical biheteroarenes bearing structural motifs of substantial utility in organic synthesis.