1389252-37-2

Basic information

• Product Name: 3-phenyl-2,3,6,7-tetrahydroimidazo[2,1-b]thiazolo[5,4-d]isoxazole
• CAS NO: 1389252-37-2
• Molecular Weight: 245.305
• Mol File: 1389252-37-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-phenyl-2,3,6,7-tetrahydroimidazo[2,1-b]thiazolo[5,4-d]isoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenyl-2,3,6,7-tetrahydroimidazo[2,1-b]thiazolo[5,4-d]isoxazole(1389252-37-2)
• EPA Substance Registry System: 3-phenyl-2,3,6,7-tetrahydroimidazo[2,1-b]thiazolo[5,4-d]isoxazole(1389252-37-2)

Safety Data

• Hazardous Substances Data: 1389252-37-2(Hazardous Substances Data)

Upstream product

• 17886-71-4 (Z)-2-benzylidene-5,6-dihydroimidazo[2,1-b]thiazol-3(2H)-one 

Relevant articles and documents

Synthesis of some novel fused imidazo [2, 1-b] [1, 3] thiazole and imidazo [2, 1-b] thiazolo [5, 4-d] isoxazole derivatives

In this work we describe the synthesis of some novel fused imidazo [2, 1-b] [1, 3] thiazole derivatives. The reaction of 1, 2-diaminoethane 1 with carbon disulphide in H2O/ETOH as solvent furnishes 4, 5-dihydro-1H-imidazol- 2-thiol 2 under reflux condition. the reaction of 4, 5-dihydro-1H-imidazol-2- thiol on treatment with ethylchloro acetate and aromatic aldehyde in presence of anhydrous sodium acetate and acetic acid as solvent to give (Z)-2- (arylidene)-5, 6-dihydroimidazo [2, 1-b] [1, 3] thiazol-3 (2H)-one 3a-j. Compounds 3a-j was condensed with hydroxylamine to give 3- (aryl)-2, 3, 6, 7-tetrahydroimidazo [2, 1-b] [1, 3] thiazolo [5, 4-d] isoxazole 4a-j. The structures of the new compounds were established by elemental analyses, IR, 1H NMR and 13C NMR data.