138964-56-4Relevant articles and documents
ANTI-CANCER AGENTS AND ANDROGEN INHIBITION ACTIVITY COMPOUND
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Page/Page column 29, (2008/12/06)
A qualitative 3D pharmacophore model (a common feature based model or Catalyst HipHop algorithm) developed from well-known natural product androgen receptor down-regulating agents (ARDAs). The 3D pharmacophore model is used as a template in virtual screening compounds for new ARDAs. ARDA compounds and compounds that strongly inhibit the growth of human prostate LNCaP cells. The compounds may be used in compositions and methods of inhibiting cell proliferation of a cancer and methods of preventing or treating cancer, including prostate cancer.
Synthesis of certain sulphonamides and aminopyranoquinoline derivatives from 4-hydroxyquinoline with biological interest
Fadda,Khalil,El-Habbal
, p. 743 - 744 (2007/10/02)
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