138990-69-9

Basic information

• Product Name: 4-Thiazoleacetamide, 2-(1-acetyl-2-oxopropylidene)-2,3-dihydro-N,3-diphenyl-
• CAS NO: 138990-69-9
• Molecular Formula: C22H20N2O3S
• Molecular Weight: 392.478
• Mol File: 138990-69-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Thiazoleacetamide, 2-(1-acetyl-2-oxopropylidene)-2,3-dihydro-N,3-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Thiazoleacetamide, 2-(1-acetyl-2-oxopropylidene)-2,3-dihydro-N,3-diphenyl-(138990-69-9)
• EPA Substance Registry System: 4-Thiazoleacetamide, 2-(1-acetyl-2-oxopropylidene)-2,3-dihydro-N,3-diphenyl-(138990-69-9)

Safety Data

• Hazardous Substances Data: 138990-69-9(Hazardous Substances Data)

Upstream product

• 1205-74-9 4-bromo-3-oxo-N-phenylbutanamide 
• 103-72-0 phenyl isothiocyanate 
• 123-54-6 acetylacetone 

Relevant articles and documents

γ-BROMOACETOACETANILIDES IN HETEROCYCLIC SYNTHESIS: A CONVENIENT SYNTHESIS OF POLYFUNCTIONALLY SUBSTITUTED 2,3-DIHYDROTHIAZOLE, PYRIDIN-2-ONE, 1,2,3-TRIAZINE, OXAZOLOPYRIDINE AND PYRAZOLOPYRIDINE DERIVATIVES

The active methylene reagents 1a-d reacted with phenyl isothiocyanate in basic DMF at room temperature to yield the non-isolable 1:1 adducts 2a-d.In situ cyclization of the latter with γ-bromoacetoanilides afforded the 2,3-dihydrothiazoles 3a-h.The reacti