1390681-87-4Relevant articles and documents
Synthesis, biological evaluation and molecular docking studies of 3-(1,3-diphenyl-1H-pyrazol-4-yl)-N-phenylacrylamide derivatives as inhibitors of HDAC activity
Li, Xi,Liu, Jia-Lin,Yang, Xian-Hui,Lu, Xiang,Zhao, Ting-Ting,Gong, Hai-Bin,Zhu, Hai-Liang
, p. 4430 - 4436 (2012/08/29)
In present study, a series of 3-(1,3-diphenyl-1H-pyrazol-4-yl)-N- phenylacrylamide derivatives (5a-8d) were designed, synthesized, and evaluated for HDAC inhibition and tumor cell antiproliferation. All of these compounds are reported for the first time,