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139087-53-9

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139087-53-9 Usage

Description

TYRPHOSTIN B48 is a small molecule inhibitor that targets the epidermal growth factor receptor (EGF-R) and plays a significant role in various cellular processes, including cell growth, proliferation, and differentiation. It is a potent inhibitor of EGF-R, making it a valuable compound for research and therapeutic applications.

Uses

Used in Pharmaceutical Industry:
TYRPHOSTIN B48 is used as a research tool for studying the role of EGF-R in cell signaling pathways and its involvement in various diseases, particularly cancer. It helps researchers understand the mechanisms of EGF-R activation and its contribution to tumor growth and progression.
Used in Cancer Research:
TYRPHOSTIN B48 is used as an inhibitor of EGF-R for investigating its role in cancer cell growth and proliferation. By inhibiting EGF-R, it can cause cell cycle arrest at late G1 and S phase, which can be useful in understanding the underlying mechanisms of cancer development and identifying potential therapeutic targets.
Used in Drug Development:
TYRPHOSTIN B48 is used as a lead compound in the development of novel anti-cancer drugs targeting EGF-R. Its ability to inhibit EGF-R activity makes it a promising candidate for the development of targeted therapies for various types of cancer, including those driven by EGF-R overexpression or mutations.
Used in Cell Biology Research:
TYRPHOSTIN B48 is used as a cell growth inhibitor in cell biology research to study the effects of EGF-R inhibition on cell cycle progression, apoptosis, and other cellular processes. This helps researchers gain insights into the complex interplay between cell signaling pathways and the role of EGF-R in cellular homeostasis.

Check Digit Verification of cas no

The CAS Registry Mumber 139087-53-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,0,8 and 7 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 139087-53:
(8*1)+(7*3)+(6*9)+(5*0)+(4*8)+(3*7)+(2*5)+(1*3)=149
149 % 10 = 9
So 139087-53-9 is a valid CAS Registry Number.

139087-53-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide

1.2 Other means of identification

Product number -
Other names Tyrphostin B48

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:139087-53-9 SDS

139087-53-9Downstream Products

139087-53-9Relevant articles and documents

STYRYL COMPOUNDS WHICH INHIBIT EGF RECEPTOR PROTEIN TYROSINE KINASE

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, (2008/06/13)

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