139115-89-2Relevant articles and documents
Synthesis of water soluble axially disubstituted silicon (IV) phthalocyanines with alkyne & azide functionality
Bandera, Yuriy,Burdette, Mary K.,Shetzline, Jamie A.,Jenkins, Ragini,Creager, Stephen E.,Foulger, Stephen H.
, p. 72 - 79 (2016)
Phthalocyanines (Pcs) are a class of photosensitizers (PSs) with a strong tendency to aggregate in aqueous solutions, which has a negative influence on their photosensitizing ability for photodynamic therapy. Four new axially disubstituted, non-aggregated silicon phthalocyanines (SiPcs), containing azide or alkyne functional groups have been synthesized and characterized. The method of synthesis is based on the reaction of silicon phthalocyanine dichloride with variable length poly(ethylene glycol) (PEG) chains in the presence of NaH. All synthesized dyes are highly soluble in alcohols, THF, CH2 Cl2, acetone, DMF and other common polar organic solvents, with the PEGylated silicon phthalocyanines (SiPcs) also being soluble in water. Photophysical and electrochemical properties of the dyes have been investigated. The presence of alkyne or azide groups in the phthalocyanine dyes, coupled with their high aqueous solubility, make these compounds useful as building blocks in copper catalyzed Huigsen azide-alkyne cycloaddition reactions (i.e. click chemistry).
Sugar-decorated hydroxyapatite: An inorganic material bioactivated with carbohydrates
Russo, Laura,Landi, Elena,Tampieri, Anna,Natalello, Antonino,Doglia, Silvia M.,Gabrielli, Luca,Cipolla, Laura,Nicotra, Francesco
, p. 1564 - 1568 (2011)
An efficient method for the direct and covalent decoration of granules of nanostructured apatite with a sample monosaccharide is presented; the hydroxyapatite material was directly functionalised with a short azido-containing spacer arm, to which α-propargyl glucopyranoside has been chemoselectively ligated by Huisgen-type cycloaddition. The 'glycosylated' hydroxypatite was characterised by its ability to interact with glucose recognising lectins.
Synthesis of a series of ethylene glycol modified water-soluble tetrameric TPE-amphiphiles with pyridinium polar heads: Towards applications as light-up bioprobes in protein and DNA assay, and wash-free imaging of bacteria
Kumar, Vikash,Naik, Viraj G.,Das, Avijit,Basu Bal, Sourayan,Biswas, Malabika,Kumar, Nupur,Ganguly, Anasuya,Chatterjee, Amrita,Banerjee, Mainak
, p. 3722 - 3732 (2019/06/04)
Available online Development of water soluble AIE-active “light-up” bioprobes for the detection of biomacromolecules has drawn huge research interests in recent past. In this study, a series of ethylene glycol modified water soluble tetrameric tetraphenyl