139119-52-1Relevant articles and documents
1,3-Asymmetric induction via 1,5-hydrogen atom translocation reactions. Highly enantioselective synthesis of β-substituted β-amino acids
Beaulieu,Arora,Veith,Taylor,Chapell,Snieckus
, p. 8727 - 8728 (2007/10/03)
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Preparation and Assignment of Configuration of 1-Benzoyl-(2S)-tert-butyl-3-methyl-perhydropyrimidin-4-one. Useful Starting Material for the Enantioselective Synthesis of α-Substituted β-Amino Acids
Juaristi, Eusebio,Quintana, Delia
, p. 723 - 726 (2007/10/02)
(S)-Asparagine, an inexpensive β-amino acid was converted into the title heterocycle (+)-1 in very good overall yield.The highly selective trans methylation of (+)-1-Li, and the hydrolysis of the resulting adduct afforded (R)-α-methyl-β-alanine, allowing the assignment of the (S) configuration in (+)-1.