1391621-63-8Relevant articles and documents
3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)
Hsu, John T.-A.,Yeh, Teng-Kuang,Yen, Shih-Chieh,Chen, Chiung-Tong,Hsieh, Shu-Yi,Hsu, Tsu,Lu, Cheng-Tai,Chen, Chun-Hwa,Chou, Ling-Hui,Chiu, Ching-Hui,Chang, Yun-I,Tseng, Ya-Ju,Yen, Kuei-Rong,Chao, Yu-Sheng,Lin, Wen-Hsing,Jiaang, Weir-Torn
scheme or table, p. 4654 - 4659 (2012/08/07)
A new class of FLT3 inhibitors has been identified based on the 3-phenyl-1H-5-pyrazolylamine scaffold. The structure-activity relationships led to the discovery of two carbamate series, and some potent compounds within these two series exhibited better gr