1391837-83-4Relevant articles and documents
DABCO-mediated [4+2] annulation of but-3-yn-2-one and activated ketones: Facile preparation of 2,3-dihydropyran-4-one
Lian, Zhong,Zhao, Qian-Yi,Wei, Yin,Shi, Min
supporting information; experimental part, p. 3338 - 3341 (2012/07/01)
We found that nitrogen-containing Lewis base mediated [4+2] annulation of but-3-yn-2-one with activated ketones could proceed efficiently to give the corresponding 2,3-dihydropyran-4-ones in moderate to good yields under mild conditions. The substrate scope has been carefully examined. Moreover, a plausible reaction mechanism for the [4+2] annulation of but-3-yn-2-one with activated ketones mediated by DABCO has been proposed on the basis of previous literature and our own investigations. Copyright