1392445-09-8

Basic information

• Product Name: 7-bromo-6-(4-hydroxybiphenyl-4'-ylamino)quinoline-5,8-dione
• Synonyms: 7-bromo-6-(4-hydroxybiphenyl-4'-ylamino)quinoline-5,8-dione
• CAS NO: 1392445-09-8
• Molecular Weight: 421.25
• Mol File: 1392445-09-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-bromo-6-(4-hydroxybiphenyl-4'-ylamino)quinoline-5,8-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 7-bromo-6-(4-hydroxybiphenyl-4'-ylamino)quinoline-5,8-dione(1392445-09-8)
• EPA Substance Registry System: 7-bromo-6-(4-hydroxybiphenyl-4'-ylamino)quinoline-5,8-dione(1392445-09-8)

Safety Data

• Hazardous Substances Data: 1392445-09-8(Hazardous Substances Data)

Upstream product

• 521-74-4 broxyquinoline 
• 20947-47-1 7‐bromoquinoline‐5,8‐dione 
• 1204-79-1 4-amino-4'-hydroxybiphenyl 
• 148-24-3 8-quinolinol 

Relevant articles and documents

New quinoline-5,8-dione and hydroxynaphthoquinone derivatives inhibit a chloroquine resistant Plasmodium falciparum strain

We report on the design, synthesis, and in vitro evaluation of new quinoline-5,8-dione and hydroxynaphthoquinone derivatives. The synthesized compounds were evaluated for in vitro antimalarial activity against Plasmodium falciparum. Of the 15 compounds, 7a-c, 8a, 9b, 11, and 15 were effective in growth inhibition with IC50 values of below 5 μM.