1392473-17-4

Basic information

• Product Name: 4-chloro-2-hydroxy-N,N-diisopropylbenzamide
• Synonyms: 4-chloro-2-hydroxy-N,N-diisopropylbenzamide
• CAS NO: 1392473-17-4
• Molecular Weight: 255.744
• Mol File: 1392473-17-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-chloro-2-hydroxy-N,N-diisopropylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-2-hydroxy-N,N-diisopropylbenzamide(1392473-17-4)
• EPA Substance Registry System: 4-chloro-2-hydroxy-N,N-diisopropylbenzamide(1392473-17-4)

Safety Data

• Hazardous Substances Data: 1392473-17-4(Hazardous Substances Data)

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 108-18-9 diisopropylamine 
• 79606-45-4 N,N-diisopropyl 4-chlorobenzamide 

Relevant articles and documents

Direct Hydroxylation and Amination of Arenes via Deprotonative Cupration

Deprotonative directed ortho cupration of aromatic/heteroaromatic C-H bond and subsequent oxidation with t-BuOOH furnished functionalized phenols in high yields with high regio- and chemoselectivity. DFT calculations revealed that this hydroxylation reaction proceeds via a copper (I → III → I) redox mechanism. Application of this reaction to aromatic C-H amination using BnONH2 efficiently afforded the corresponding primary anilines. These reactions show broad scope and good functional group compatibility. Catalytic versions of these transformations are also demonstrated.