139308-53-5 Usage
General Description
Ethyl 1-tert-butyl-1H-pyrazole-4-carboxylate is a chemical compound with the molecular formula C10H16N2O2. It is an ester, which means it is derived from an organic acid and an alcohol, and it is commonly used in the synthesis of various pharmaceuticals and agrochemicals. Ethyl 1-tert-butyl-1H-pyrazole-4-carboxylate is known for its high stability and its ability to function as a building block in the creation of biologically active molecules. Its structure consists of a pyrazole ring with an ethyl ester and a tert-butyl group attached to it, making it a versatile and valuable intermediate in organic synthesis. The chemical's properties and structure make it an important component in the development of new drugs and agricultural products.
Check Digit Verification of cas no
The CAS Registry Mumber 139308-53-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,3,0 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 139308-53:
(8*1)+(7*3)+(6*9)+(5*3)+(4*0)+(3*8)+(2*5)+(1*3)=135
135 % 10 = 5
So 139308-53-5 is a valid CAS Registry Number.
139308-53-5Relevant articles and documents
Decarboxylative N-Alkylation of Azoles through Visible-Light-Mediated Organophotoredox Catalysis
Kobayashi, Rino,Shibutani, Shotaro,Nagao, Kazunori,Ikeda, Zenichi,Wang, Junsi,Ibá?ez, Ignacio,Reynolds, Matthew,Sasaki, Yusuke,Ohmiya, Hirohisa
supporting information, p. 5415 - 5419 (2021/07/19)
An organophotoredox-catalyzed decarboxylative cross-coupling between azole nucleophiles and aliphatic carboxylic acid-derived redox-active esters is demonstrated. This protocol efficiently installs various tertiary or secondary alkyl fragments onto the nitrogen atom of azole nucleophiles under mild and transition-metal-free conditions. The pyridinium additive successfully inhibits the formation of elimination byproducts from the carbocation intermediate. This reaction is applicable to the synthesis of a protein-degrader-like molecule containing an azole and a thalidomide.
