1393091-25-2Relevant articles and documents
Gold(I) complexes derived from alkynyloxy-substituted anthraquinones: Syntheses, luminescence, preliminary cytotoxicity, and cell imaging studies
Balasingham, Rebeca G.,Williams, Catrin F.,Mottram, Huw J.,Coogan, Michael P.,Pope, Simon J. A.
, p. 5835 - 5843 (2012)
A series of mono- and dimetallic Au(I) triphenylphosphine complexes derived from 1,2-, 1,4-, and 1,8-dialkynyloxyanthraquinone have been prepared. The photophysical and cytotoxic behavior of the ligands and complexes have been explored, with all of the complexes showing both appreciable cytotoxicity against the MCF-7 carcinoma cell line and useful room-temperature anthraquinone-based visible luminescence, which allowed their successful application as fluorophores in cell imaging microscopy. The implications of the photophysical and toxicological properties for the design and investigation of gold-based anticancer agents are discussed.
