1393712-31-6

Basic information

• Product Name: C₂₁H₂₁Cl₃O₄
• Synonyms: C₂₁H₂₁Cl₃O₄
• CAS NO: 1393712-31-6
• Molecular Weight: 443.754
• Mol File: 1393712-31-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₁Cl₃O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₁Cl₃O₄(1393712-31-6)
• EPA Substance Registry System: C₂₁H₂₁Cl₃O₄(1393712-31-6)

Safety Data

• Hazardous Substances Data: 1393712-31-6(Hazardous Substances Data)

Upstream product

• 10112-13-7 phenyl trichloroacetate 
• 41795-26-0 benzoic acid hex-5-enyl ester 

Relevant articles and documents

Microwave-assisted atom transfer radical addition of polychlorinated compounds to olefins without addition of metal catalysts

A new operationally simple and robust protocol for the metal-free atom transfer radical reaction (ATRA) has been developed. Polychlorinated compounds were effectively reacted with unactivated terminal olefins to generate 1,3-dichlorinated adducts under microwave irradiation in the presence of silicon carbide (SiC) as a heating element. The present microwave-assisted ATRA proceeds under essentially neutral conditions; thus, polar functionalities are well tolerated. In addition, an oxygen or a nitrogen unit was introduced to the internal side of the carbon chain via nucleophilic cyclization of the 1,3-dichlorinated adducts, and single-step formation of the six-membered carbocycle was realized through cyclization of the intermediate radical. The present methodology provides an expeditious way to prepare synthetically useful molecules from simple and unactivated terminal olefins.