1393817-78-1Relevant articles and documents
Rh(III)-Catalyzed N-Nitroso Directed C-H Arylation for Facile Construction of Diverse N-Hetero Biaryl Compounds
Wang, Pei-Long,Wang, Yan,Li, Yan,Wang, Xi-Sheng
, p. 3825 - 3828 (2020)
A Rh(III)-catalyzed C?H arylation reaction of N-nitrosoanilines has been developed in which arylboronic acids were used as arylation reagents. It provides an efficient strategy for the synthesis of N-nitroso-[1,1′-biphenyl]-2-amine, which is an important starting material for the synthesis of N-hetero biaryl compounds, such as 2-amine-1,1′-biphenyl, carbazole, phenanthridone. This protocol can be applied to various N-alkyl substituted N-nitrosoanilines and N-nitrosoanilines with substituents on the phenyl ring. Arylboronic acids with both electron-donating and electron-withdrawing groups are tolerated.
Ru-Catalyzed Deoxygenative Regioselective C8-H Arylation of Quinoline N-Oxides
Kim, Jinwoo,Kim, Suhyeon,Kim, Dongwook,Chang, Sukbok
, p. 13150 - 13158 (2019/08/22)
Regioselective C-H functionalization on quinolines is of high interest to lead to value-added products. Herein, we describe the development of Ru-catalyzed deoxygenative regioselective C8 arylation of quinoline N-oxides with arylboronic esters. Mechanistic studies revealed that it proceeds in a tandem process of arylation and then deoxygenation, wherein both steps were found to be catalytic with the ruthenium species.