139399-67-0 Usage
Description
3-Bromoquinolin-8-amine is an organic compound with the molecular formula C9H8BrN3. It is a derivative of quinoline, a nitrogen-containing aromatic compound, and features a bromine atom at the 3-position and an amine group at the 8-position. 3-BROMOQUINOLIN-8-AMINE is known for its potential applications in the pharmaceutical industry due to its unique chemical structure and properties.
Uses
Used in Pharmaceutical Industry:
3-Bromoquinolin-8-amine is used as a reagent for the synthesis of various compounds with potential therapeutic applications. Its role in the development of new drugs makes it a valuable component in the pharmaceutical industry.
Used in Alzheimer's Disease Treatment:
3-Bromoquinolin-8-amine is used as a reagent for the synthesis of 3-(arylsulfonyl)-8-(piperidin-4-yl amino)quinoline derivatives, which are known as 5-HT6 receptor antagonists. These antagonists have the potential to treat Alzheimer's disease by modulating the serotonin receptor, which is implicated in the cognitive decline associated with the condition.
Used in Schizophrenia Treatment:
Similarly, 3-Bromoquinolin-8-amine is utilized in the synthesis of compounds that target the 5-HT6 receptor, which is also involved in the pathology of Schizophrenia. By developing antagonists for this receptor, it may be possible to alleviate some of the symptoms associated with this mental health disorder.
Used in Antimalarial Drug Synthesis:
3-Bromoquinolin-8-amine also serves as a reagent for the synthesis of certain 8-aminoquinolines, which are known for their antimalarial properties. These compounds can be used to develop new drugs to combat malaria, a disease that affects millions of people worldwide.
Check Digit Verification of cas no
The CAS Registry Mumber 139399-67-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,3,9 and 9 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 139399-67:
(8*1)+(7*3)+(6*9)+(5*3)+(4*9)+(3*9)+(2*6)+(1*7)=180
180 % 10 = 0
So 139399-67-0 is a valid CAS Registry Number.
139399-67-0Relevant articles and documents
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Hauser et al.
, p. 1544 (1946)
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PHENANTHROLINE PHOSPHONIC ACID DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
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Paragraph 0093-0095, (2017/02/28)
The present invention relates to a novel phenanthroline phosphonic acid compound and a pharmaceutical salt thereof, as well as an application of the compound and the pharmaceutical salt thereof as collagen prolyl hydroxylase inhibitors in the preparation of drugs for preventing or treating collagen prolyl-4-hydroxylase related disease.
QUINOLINE DERIVATIVES FOR DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE
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Page/Page column 12, (2016/11/28)
A new class of quinoline compounds is useful for the detection and treatment of Alzheimer's disease and other neurodegenerative diseases such as amyloidoses and tauopathies. The compounds can be synthesized in radiolabeled form for use as imaging agents,
