139416-71-0

Basic information

• Product Name: Benzenemethanol, a-ethynyl-2-methyl-
• Synonyms: 1-(o-tolyl)-2-propyn-1-ol;1-o-tolyl-2-propyn-1-ol;1-(o-methylphenyl)-2-propyn-1-ol;1-(ortho-tolyl)-2-propyn-1-ol;1-o-Tolyl-prop-2-yn-1-ol
• CAS NO: 139416-71-0
• Molecular Formula: C10H10O
• Molecular Weight: 146.189
• Mol File: 139416-71-0.mol
• Article Data: 29

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-ethynyl-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-ethynyl-2-methyl-(139416-71-0)
• EPA Substance Registry System: Benzenemethanol, a-ethynyl-2-methyl-(139416-71-0)

Safety Data

• Hazardous Substances Data: 139416-71-0(Hazardous Substances Data)

Upstream product

• 529-20-4 2-methylphenyl aldehyde 
• 4301-14-8 acetylenemagnesium bromide 
• 1066-54-2 trimethylsilylacetylene 
• 4039-82-1 Benzyl propargyl ether 

Downstream Products

• 82158-24-5 o-methylphenyl(benzofuran-2-yl)methanol 
• 153865-93-1 5-<3-hydroxy-3-(o-tolyl)prop-1-ynyl>-3',5'-di-O-(p-toluoyl)-2'-deoxyuridine 
• 148564-93-6 2-[3-hydroxy-3-(o-methylphenyl)prop-1-ynyl]trifluoroacetanilide 
• 179248-97-6 Chloro-acetic acid 1-o-tolyl-prop-2-ynyl ester 
• 1027588-01-7 Acetic acid 2-[5-(3-hydroxy-3-o-tolyl-prop-1-ynyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethoxy]-ethyl ester 
• 249509-29-3 5-[3-hydroxy-3-(o-tolyl)prop-1-ynyl]-2,4-dimethoxypyrimidine 
• 1262149-04-1 2-oxo-1-o-tolylpropyl acetate 
• 1352957-89-1 (3-o-tolylpent-1-en-4-yne-1,1-diyl)dibenzene 
• 26155-19-1 (2E)-3-(2-methylphenyl)-2-propenenitrile 

Relevant articles and documents

Allenylidene Induced 1,2-Metalate Rearrangement of Indole-Boronates: Diastereoselective Access to Highly Substituted Indolines

A process to achieve 1,2-metalate rearrangements of indole boronate as a way to access substituted indolines in high diastereoselectivities is presented. The reaction involves the generation of a Cu–allenylidene, which is sufficiently electrophilic to induce the 1,2-metalate rearrangement. The scope of the reaction is evaluated as well as further transformations of the product.

Photoinitiated anti-Hydropentafluorosulfanylation of Terminal Alkynes

A photoinitiated anti-hydropentafluorosulfanylation of terminal alkynes using SF5Cl and (TMS)3SiH as the hydrogen atom donor is reported. This transformation generates selectively (Z)-(1-alken-1-yl)pentafluoro-λ6-sulfanes

Palladium-catalyzed [3+2] annulation of allenyl carbinol acetates with C,N-cyclic azomethine imines

In this paper, a palladium-catalyzed [3+2] annulation of allenyl carbinol acetates with azomethine imines has successfully been developed under mild reaction conditions, affording biologically interesting tetrahydropyrazoloisoquinoline derivatives in high to excellent yields and with excellent stereoselectivity. The reaction follows a tandem [3+2] cycloaddition/allylation/elimination of AcOH pathway. Allenyl carbinol acetates also reacted well with in situ generated azomethine imine under cocatalysis of Ag(i)/Pd(0) catalysts in a similar reaction pathway.