139437-24-4Relevant articles and documents
Identification and optimization of tetrahydro-2H-3-benzazepin-2-ones as squalene synthase inhibitors
Griebenow, Nils,Flessner, Timo,Buchmueller, Anja,Raabe, Martin,Bischoff, Hilmar,Kolkhof, Peter
scheme or table, p. 2554 - 2558 (2011/05/15)
Novel squalene synthase inhibitors are disclosed. SAR and pharmacological profile of selected compounds are discussed.
Synthesis of novel tetrahydrobenzazepinones
Busacca, Carl A.,Johnson, Robert E.
, p. 165 - 168 (2007/10/02)
The synthesis of novel tetrahydrobenzazepinones 1, 2, and 3 is described, as well as an improved synthesis of 4. The palladium catalyzed arylation approach to 1, 2, and 4 allows facile entry to benzazepinones lacking electron donating substituents on the