139438-48-5 Usage
Molecular Structure
1H-Pyrazolo[3,4-d]pyrimidine, 3-chloro-6-phenylis a chemical compound with a specific molecular structure that belongs to the pyrazolopyrimidine class of compounds.
Chlorine Atom
This compound contains a chlorine atom at the 3 position, which can affect its chemical properties and reactivity.
Phenyl Group
The presence of a phenyl group at the 6 position can influence the compound's chemical and physical properties, including its solubility and stability.
Research and Pharmaceutical Applications
1H-Pyrazolo[3,4-d]pyrimidine, 3-chloro-6-phenylis used in various research and pharmaceutical applications, including as a building block in the synthesis of other compounds or as a potential drug candidate for the treatment of various diseases.
Medicinal Chemistry and Drug Discovery
The unique structure and properties of this chemical compound make it a valuable tool in the field of medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 139438-48-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,4,3 and 8 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 139438-48:
(8*1)+(7*3)+(6*9)+(5*4)+(4*3)+(3*8)+(2*4)+(1*8)=155
155 % 10 = 5
So 139438-48-5 is a valid CAS Registry Number.
139438-48-5Relevant articles and documents
Tricyclic Heteroaromatic Systems Containing a Bridgehead Nitrogen Atom. Part 3. Triazolopyrazolopyrimidines, Tetrazolopyrazolopyrimidines and Pyrimidopyrazolotriazines
Golec, Julian M. C.,Scrowston, Richard M.,Dunleavy, Michael
, p. 239 - 244 (2007/10/02)
6-Phenyl-1H-pyrazolopyrimidin-3(2H)-one 16 has been prepared and converted into its 3-chloro 6, 3-thioxo 17 and 3-methylthio derivatives 9.Each of these could be converted into the 3-hydrazino derivative 3, cyclisation of which with carbon disulfide or triethyl orthoformate generated the fused 1,2,4-triazoles 23 and 20, respectively.Alternatively, the hydrazino derivative 3 gave a substituted hydrazide 26 or thiosemicarbazide 25, from which the 1,2,4-triazoles 21 and 22 respectively were obtained.The equilibrium between 3-azido-6-phenyl-1H-pyrazolopyrimidine 5 and 2-phenyl-9H-tetrazolopyrazolopyrimidine 27 was studied. 3-Diazo-4-methyl-6-phenyl-1H-pyrazolopyrimidine 29 was prepared by diazotisation of the corresponding amine 1 and converted into the 3-azido compound 4, which could not be cyclised to form a tetrazole.Finally, the diazo compound 29 readily formed the pyrimidopyrazolotriazine derivatives 32 and 33, when treated with pentane-2,4-dione and ethyl acetoacetate respectively.
