13945-01-2

Basic information

• Product Name: 2-(2-chlorophenyl)-2,3-dihydro-1,3-benzothiazole
• CAS NO: 13945-01-2
• Molecular Formula: C₁₃H₁₀ClNS
• Molecular Weight: 247.7432
• Mol File: 13945-01-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 382.3°C at 760 mmHg
• Flash Point: 185°C
• Density: 1.302g/cm³
• Vapor Pressure: 4.76E-06mmHg at 25°C
• Refractive Index: 1.658
• CAS DataBase Reference: 2-(2-chlorophenyl)-2,3-dihydro-1,3-benzothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-chlorophenyl)-2,3-dihydro-1,3-benzothiazole(13945-01-2)
• EPA Substance Registry System: 2-(2-chlorophenyl)-2,3-dihydro-1,3-benzothiazole(13945-01-2)

Safety Data

• Hazardous Substances Data: 13945-01-2(Hazardous Substances Data)

Usage

Classification

Benzothiazole derivative, phenylpropanoid

Biological activities

Anti-inflammatory, antioxidant, anti-cancer, potential treatment for neurodegenerative diseases, cardiovascular conditions

Other potential uses

Food preservative, antimicrobial agent, drug delivery vehicle, enhancer of solubility for certain pharmaceutical compounds

Versatility

Shown potential in various fields, including medicine and food science.

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 137-07-5 2-amino-benzenethiol 
• 128921-61-9 N-(2-chlorobenzylidene)-o-amino-thiophenol 

Downstream Products

• 98123-32-1 trans-2-benzoyl-3-(2-chlorophenyl)-2,3-dihydro-1,4-benzothiazine 
• 98123-32-1 [(2R,3R)-3-(2-Chloro-phenyl)-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl]-phenyl-methanone 
• 100067-18-3 2-(2-Chloro-benzylamino)-benzenethiol 
• 6269-46-1 2-(2-chlorophenyl)-1,3-benzothiazole 
• 100067-25-2 C₂₆H₂₂Cl₂N₂S₂ 

Relevant articles and documents

Pentafluorophenylammonium Triflate: A Mild, Efficient and Reusable Catalyst for the Synthesis of 2-Arylbenzothiazole and 2-Arylbenzothiazoline Derivatives in a Green Chemical Approach

In this work, one pot, simple and environmentally benign effective synthesis of 2-substituted benzothiazole and benzothiazoline derivatives are described in presence of PFPAT (pentafluorophenylammonium triflate) catalyst in water successfully. A series of benzothiazole derivative were synthesized by the reaction between 2-aminothiophenol and various aldehydes in good yields. Recyclability of the catalyst is observed for four times without loss of its activity in aqueous medium.

Efficient 2,4,6-trichloro-1,3,5-triazine-catalyzed synthesis of 2-arylbenzothiazoles and bisbenzothiazoles by condensation of 2-aminithiophenol with aldehydes under mild conditions

2,4,6-Trichloro-1,3,5-triazine efficiently catalyzed the condensation reactions between 2-aminothiophenol and aromatic aldehydes to afford 2-arylbenzothiazolles in good-to-excellent yields. Simple and mild reaction conditions, the use of a cheap catalyst

A green method for the synthesis of 2-arylbenzoles

Aromatic aldehydes with both electron withdrawing and electron donating substituents were smoothly converted to the corresponding 2-arylbenzothiazoles by direct condensation of aromatic aldehydes with 2-aminothiophenol in one pot in a microoven under solv