139524-61-1

Basic information

• Product Name: 1,8-Naphthyridine-3-carboxylic acid, 1-(2,4-difluorophenyl)-7-(1,4-dioxa-7-azaspiro[4.4]non-7-yl)-6-fluoro-1,4 -dihydro-4-oxo-, ethyl ester
• CAS NO: 139524-61-1
• Molecular Formula: C23H20F3N3O5
• Molecular Weight: 475.424
• Mol File: 139524-61-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,8-Naphthyridine-3-carboxylic acid, 1-(2,4-difluorophenyl)-7-(1,4-dioxa-7-azaspiro[4.4]non-7-yl)-6-fluoro-1,4 -dihydro-4-oxo-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8-Naphthyridine-3-carboxylic acid, 1-(2,4-difluorophenyl)-7-(1,4-dioxa-7-azaspiro[4.4]non-7-yl)-6-fluoro-1,4 -dihydro-4-oxo-, ethyl ester(139524-61-1)
• EPA Substance Registry System: 1,8-Naphthyridine-3-carboxylic acid, 1-(2,4-difluorophenyl)-7-(1,4-dioxa-7-azaspiro[4.4]non-7-yl)-6-fluoro-1,4 -dihydro-4-oxo-, ethyl ester(139524-61-1)

Safety Data

• Hazardous Substances Data: 139524-61-1(Hazardous Substances Data)

Upstream product

• 139524-57-5 N-(benzyloxycarbonyl)-7-aza-1,4-dioxospiro<4.4>nonane 
• 100491-29-0 ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate 
• 176-33-0 1,4-dioxa-6-azaspiro[4.4]nonane 

Downstream Products

• 139524-72-4 7-<3-(methoxyimino)pyrrolidinyl>-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid 

Relevant articles and documents

Preparation and in Vitro and in Vivo Evaluation of Quinolones with Selective Activity against Gram-Positive Organisms

A series of quinolones were prepared which contained oximes or substituted oximes as replacements for the amine substituents normally found on the pyrrolidine or piperidine fragments of quinolone antibacterial agents.These substituents led to compounds that had selective activity against Gram-positive organisms.These compounds showed in vivo activity Staphylococcus aureus.Only compound 29 had in vivo activity against Streptococcus pneumoniae.