139551-83-0 Usage
Description
FMOC-L-LEUCINOL, also known as 9-fluorenylmethoxycarbonyl-L-leucinol, is a synthetic compound commonly utilized in the field of organic chemistry and pharmaceuticals. It is a white powder with specific chemical properties that make it a valuable intermediate in the synthesis of various compounds.
Uses
Used in Pharmaceutical Industry:
FMOC-L-LEUCINOL is used as an intermediate for the preparation of Fmoc-protected amino azides from Fmoc-protected amino alcohols. This application is crucial in the development of new pharmaceutical compounds, as it aids in the synthesis of complex molecules with potential therapeutic properties.
Used in Organic Chemistry:
In the field of organic chemistry, FMOC-L-LEUCINOL serves as a key building block for the creation of various organic compounds. Its unique structure allows for the formation of new chemical bonds and the synthesis of molecules with specific functionalities, which can be further explored for their potential applications in different industries.
Used in Research and Development:
FMOC-L-LEUCINOL is also employed in research and development laboratories, where it is used to study the properties and reactivity of Fmoc-protected amino alcohols and their derivatives. This knowledge can be applied to the design and synthesis of novel compounds with potential applications in various fields, such as medicine, agriculture, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 139551-83-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,5,5 and 1 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 139551-83:
(8*1)+(7*3)+(6*9)+(5*5)+(4*5)+(3*1)+(2*8)+(1*3)=150
150 % 10 = 0
So 139551-83-0 is a valid CAS Registry Number.
139551-83-0Relevant articles and documents
A practical solid phase synthesis of oligopeptidosulfonamide foldamers
Monnee,Marijne,Brouwer,Liskamp
, p. 7991 - 7995 (2000)
Oligopeptidosulfonamide foldamers were efficiently synthesized on the solid phase using Fmoc protected β-aminoethanesulfonylchlorides in the presence of N-methylmorpholine. (C) 2000 Elsevier Science Ltd.
A greener, efficient and catalyst-free ultrasonic-assisted protocol for the n-fmoc protection of amines
Mansouri, Rachida,Aouf, Zineb,Lakrout, Salah,Berredjem, Malika,Aouf, Nour-Eddine
, p. 546 - 550 (2016/03/19)
A simple, eco-sustainable method for the N-(9-fluorenylmethoxycarbonyl) (N-Fmoc) protection of various structurally amines under ultrasonic irradiation is reported. The corresponding N-Fmoc derivatives were obtained in good to excellent yields within short reaction time. The reaction proceeds without the formation of any side product. Mildness, efficiency and easier work are the main advantages of this new protocol.
Alzheimer's disease: Identification and development of β-secretase (BACE-1) binding fragments and inhibitors by dynamic ligation screening (DLS)
Fernandez-Bachiller, Maria Isabel,Horatscheck, Andre,Lisurek, Michael,Rademann, Joerg
, p. 1041 - 1056 (2013/07/26)
The application of dynamic ligation screening (DLS), a methodology for fragment-based drug discovery (FBDD), to the aspartic protease β-secretase (BACE-1) is reported. For this purpose, three new fluorescence resonance energy transfer (FRET) substrates we
