139579-42-3

Basic information

• Product Name: Benzaldehyde, 5-methoxy-2-[(3-methyl-2-butenyl)oxy]-
• CAS NO: 139579-42-3
• Molecular Formula: C13H16O3
• Molecular Weight: 220.268
• Mol File: 139579-42-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 5-methoxy-2-[(3-methyl-2-butenyl)oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 5-methoxy-2-[(3-methyl-2-butenyl)oxy]-(139579-42-3)
• EPA Substance Registry System: Benzaldehyde, 5-methoxy-2-[(3-methyl-2-butenyl)oxy]-(139579-42-3)

Safety Data

• Hazardous Substances Data: 139579-42-3(Hazardous Substances Data)

Upstream product

• 672-13-9 2-hydroxy-5-methoxybenzaldehyde 
• 870-63-3 prenyl bromide 
• 67-64-1 acetone 

Downstream Products

• 206664-30-4 2-methyl-4-[2-(1-hydroxyprop-2-yn-1-yl)-4-methoxyphenoxy]but-2-ene 

Relevant articles and documents

A nickel(ii)-catalyzed asymmetric intramolecular Alder-ene reaction of 1,7-dienes

A highly diastereo- and enantioselective intramolecular Alder-ene reaction with an alkene as the enophile has been developed by using a chiral N,N′-dioxide/nickel(ii) complex as the catalyst. This protocol provides a facile route towards the synthesis of diverse 3,4-disubstituted chroman, tetrahydroquinoline, piperidine and thiochroman derivatives in high yields with good to excellent diastereo- and enantioselectivities.

ABCA1 elevating compounds

The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCA1 production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrom

A diastereoselective cobalt-mediated synthesis of benzopyrans using a novel variation of an intramolecular Nicholas reaction in the key cyclisation step: Optimisation and biological evaluation

A range of novel intramolecular cyclisation reactions between an organocobalt stabilised cation and a trisubstituted alkene have been accomplished that provide a concise route for the diastereoselective synthesis of a range of functionalised benzopyrans. In addition to the usual Lewis acids employed in the Nicholas reaction our studies have identified several other reagents for effecting the cyclisation reaction. In some examples sub-stoichiometric quantities of Lewis acid were successfully employed. These studies were concluded with a biological evaluation of specific derivatives, conducted by comparing their activity with the antihypertensive agent cromakalim 2, a drug whose mode of action is known to occur via the modulation of potassium channel activity.