139605-59-7

Basic information

• Product Name: 5-methyl-3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzothiazin-2(1H)-one
• CAS NO: 139605-59-7
• Molecular Formula: C₁₁H₁₁N₃OS
• Molecular Weight: 233.2895
• Mol File: 139605-59-7.mol
• Article Data: 1

Chemical Properties

• Density: 1.5g/cm³
• Refractive Index: 1.763
• CAS DataBase Reference: 5-methyl-3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzothiazin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzothiazin-2(1H)-one(139605-59-7)
• EPA Substance Registry System: 5-methyl-3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzothiazin-2(1H)-one(139605-59-7)

Safety Data

• Hazardous Substances Data: 139605-59-7(Hazardous Substances Data)

Upstream product

• 100598-55-8 ethyl 2-methyl-2H-1,4-benzothiazin-3-one-4-acetate 
• 137-07-5 2-amino-benzenethiol 
• 7028-57-1 2-methyl-3,4-dihydro-3-oxo-2H-1,4-benzothiazine 
• 473477-34-8 (2-methyl-3-oxo-2,3-dihydro-benzo[1,4]thiazin-4-yl)-acetic acid hydrazide 

Relevant articles and documents

Synthesis of some new tricyclic 1,4-benzothiazinones

2-Aminothiophenol on reaction with dimethyl oxalate and methyl 2-chloropropionate gives 1,4-benzothiazinone, (1a, 1b) which when reacted with ethyl chloroacetate give N-ethoxycarbonylmethyl-1,4-benzothiazine-2,3-dione (2a1). Compound 2 on reaction with hydrazine hydrate affords N-hydrazidomethyl-1,4-benzothiazine-2,3-dione (3). Compound 3 is cyclized in presence of ammonium acetate and acetic acid to give 5-methyl[1,2,4]triazino-6-oxo[3,4-c]-3(1H)-[1,4]benzothiazine (4b1). Compound 1 on reaction with phosphorus oxychloride gives 3-chloro-1,4-benzothiazine-3-one (5a) which when reacts with ammonium sulfocyanide affords 1,4-benzothiazin-2-one-3-ylisocyanate (6a). Compound 6 when reacted with methyl cyanide gives the desired tricyclic compound 2-thio-6-methyl[1,3,5]triazolo[3,4-c]benzothiazine-2-one (7a).