13964-47-1

Basic information

• Product Name: 5-fluoro-6-methoxy-5,6-dihydrouracil
• Synonyms: 5-fluoro-6-methoxy-5,6-dihydrouracil
• CAS NO: 13964-47-1
• Molecular Weight: 162.121
• Mol File: 13964-47-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-fluoro-6-methoxy-5,6-dihydrouracil(CAS DataBase Reference)
• NIST Chemistry Reference: 5-fluoro-6-methoxy-5,6-dihydrouracil(13964-47-1)
• EPA Substance Registry System: 5-fluoro-6-methoxy-5,6-dihydrouracil(13964-47-1)

Safety Data

• Hazardous Substances Data: 13964-47-1(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 51-21-8 5-fluorouracil 
• 56311-36-5 6-Acetoxy-5-fluoro-5,6-dihydrouracil 
• 66-22-8 uracil 
• 56311-36-5 cis-5-fluoro-6-acetoxy-5,6-dihydrouracil 

Downstream Products

• 51-21-8 5-fluorouracil 
• 66-22-8 uracil 

Relevant articles and documents

Photochemical reactions of 5-fluoropyrimidine bases with alcohols

Photochemical reactions of 5-fluorocytosine with primary alcohols led to 5-alkoxycytosines and 6-alkoxycytosines as the main photoproducts. These products are formed via reactive intermediates 6-alkoxy-5-fluoro-5,6- dihydrocytosines, whereas photochemical reactions of 5-fluorouracil with alcohols led to stable 6-alkoxy-5-fluoro-5,6-dihydrouracils.

SYNTHESIS AND PROPERTIES OF 5-FLUORO-6-ALKOXY URACIL DERIVATIVES; FORMATION OF A HIGH AMOUNT OF 'ANTI-GAUCHE'PRODUCTS.

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Process for preparation of 6-substituted 5-fluorouracil derivatives

The reaction of certain fluorinated pyrimidine derivatives with hydrogen donor compounds to produce 6-substituted 5-fluoropyrimidines is disclosed. The products so produced are useful in germicidal and antineoplastic applications, and can be converted into 5-fluorouracil, which has known utility in cancer chemotherapy.