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1396788-43-4

1396788-43-4

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1396788-43-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1396788-43-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,6,7,8 and 8 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1396788-43:
(9*1)+(8*3)+(7*9)+(6*6)+(5*7)+(4*8)+(3*8)+(2*4)+(1*3)=234
234 % 10 = 4
So 1396788-43-4 is a valid CAS Registry Number.

1396788-43-4Downstream Products

1396788-43-4Relevant articles and documents

Disubstituted piperidines as potent orexin (hypocretin) receptor antagonists

Jiang, Rong,Song, Xinyi,Bali, Purva,Smith, Anthony,Bayona, Claudia Ruiz,Lin, Li,Cameron, Michael D.,McDonald, Patricia H.,Kenny, Paul J.,Kamenecka, Theodore M.

, p. 3890 - 3894 (2012/07/13)

A series of orexin receptor antagonists was synthesized based on a substituted piperidine scaffold. Through traditional medicinal chemistry structure-activity relationships (SAR), installation of various groups at the 3-6-positions of the piperidine led to modest enhancement in receptor selectivity. Compounds were profiled in vivo for plasma and brain levels in order to identify candidates suitable for efficacy in a model of drug addiction.

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