139684-85-8Relevant articles and documents
Enantioselective Catalysis, VIII. - New 1,2-Bisphosphane Ligands with Four Stereogenic Centers and Additional Methoxy Groups for Asymmetric Catalytic Hydrogenation
Nagel, Ulrich,Bublewitz, Alexander
, p. 1061 - 1072 (2007/10/02)
The synthesis of N-acyl derivatives of all possible diastereomers of -3,4-bispyrrolidine and -3,4-bispyrrolidine in optical pure form is described.Palladium and rhodium complexes with these ligands were prepared.The enantioselective hydrogenation of acetamidocinnamic acid with these rhodium complexes was studied at H2 pressures between 1 and 75 bar.There is only a small influence of the 2-methoxy group in the ligand on the catalytic hydrogenation when compared with the respective unsubstituted diastereomer.Te structure of pyrrolidine-P,P'>diiodopalladium was determined by X-ray diffraction.Key Words: 3,4-Bis(phosphanyl)pyrrolidines / Palladium complexes / Rhodium complexes / Asymmetric hydrogenation
