1398056-84-2Relevant articles and documents
Synthesis of non-symmetrical 3,4-diaryl-substituted pyrroles: Implementation for the preparation of lamellarin R
Zavala-Gómez, Héctor,Ramírez-Rodríguez, Armando,Vázquez, Alfredo
, p. 677 - 683 (2018/01/08)
A straightforward method for synthesising symmetrical and non-symmetrical 3,4-diaryl-substituted pyrroles is proposed, consisting of (i) the condensation reaction between phenylacetonitriles and aldehydes to give acrylonitriles, (ii) the conjugate additio
2,4- vs 3,4-disubsituted pyrrole synthesis switched by copper and nickel catalysts
Chen, Feng,Shen, Tao,Cui, Yuxin,Jiao, Ning
supporting information, p. 4926 - 4929,4 (2012/12/12)
A novel and efficient copper or nickel catalyzed highly selective denitrogenative annulation of vinyl azides with aryl acetaldehydes has been developed. 2,4- and 3,4-diaryl substituted pyrroles, which are difficult to synthesize by the reported methods, can be highly regioselectively prepared by this protocol simply switched by the selection of the transition metal catalysts. Compared with the reported acidic or basic conditions for polysubstituted pyrrole synthesis, the present reaction conditions are mild, neutral, and very simple without any additives.