1398508-11-6

Basic information

• Product Name: dimethyl 2-((S)-((S)-2-oxocyclohexyl)(thiophen-2-yl)methyl)malonate
• CAS NO: 1398508-11-6
• Molecular Weight: 324.398
• Mol File: 1398508-11-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: dimethyl 2-((S)-((S)-2-oxocyclohexyl)(thiophen-2-yl)methyl)malonate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2-((S)-((S)-2-oxocyclohexyl)(thiophen-2-yl)methyl)malonate(1398508-11-6)
• EPA Substance Registry System: dimethyl 2-((S)-((S)-2-oxocyclohexyl)(thiophen-2-yl)methyl)malonate(1398508-11-6)

Safety Data

• Hazardous Substances Data: 1398508-11-6(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 72796-68-0 dimethyl 2‐(thiophen‐2‐ylmethylene)malonate 

Relevant articles and documents

Highly enantioselective conjugate addition of ketones to alkylidene malonates catalyzed by a pyrrolidinyl-camphor-derived organocatalyst

Pyrrolidinyl-camphor derivatives have been proven to be efficient organocatalysts for enantioselective conjugate addition of ketones to alkylidene malonates, affording high chemical yields (up to 95 %) of the corresponding products with high to excellent levels of diastereoselectivity (up to >99:1 dr) and enantioselectivity (up to 96%ee) under solvent-free reaction conditions at ambient temperature.