139888-25-8

Basic information

• Product Name: Uridine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 5'-benzoate
• CAS NO: 139888-25-8
• Molecular Formula: C22H30N2O6Si
• Molecular Weight: 446.575
• Mol File: 139888-25-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Uridine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 5'-benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Uridine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 5'-benzoate(139888-25-8)
• EPA Substance Registry System: Uridine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 5'-benzoate(139888-25-8)

Safety Data

• Hazardous Substances Data: 139888-25-8(Hazardous Substances Data)

Upstream product

• 65-85-0 benzoic acid 
• 14270-73-6 O^5'-trityl-2'-deoxy-uridine 
• 859206-64-7 1-[(2R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-trityloxymethyl-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione 
• 951-78-0 2'-deoxyuridine 
• 98-88-4 benzoyl chloride 
• 76223-05-7 1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione 
• 123606-62-2 5'-O-Benzoyl-2'-desoxy-β-D-ribofuranosyluracil 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 123606-62-2 5'-O-Benzoyl-2'-desoxy-β-D-ribofuranosyluracil 
• 139888-13-4 4'-Cyano-2'-deoxycytidine 

Relevant articles and documents

Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target

This paper describes a structure-activity study to identify novel, small-molecule inhibitors of the enzyme deoxyuridine 5′-triphosphate nucleotidohydrolase (dUTPase) from parasitic protozoa. The successful synthesis of a variety of analogues of dUMP is de