1400562-30-2

Basic information

• Product Name: phenyl 2,6-di-O-benzyl-3,4-di-O-chloroacetyl-1-thio-β-D-galactopyranoside
• Synonyms: phenyl 2,6-di-O-benzyl-3,4-di-O-chloroacetyl-1-thio-β-D-galactopyranoside
• CAS NO: 1400562-30-2
• Molecular Weight: 605.536
• Mol File: 1400562-30-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: phenyl 2,6-di-O-benzyl-3,4-di-O-chloroacetyl-1-thio-β-D-galactopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl 2,6-di-O-benzyl-3,4-di-O-chloroacetyl-1-thio-β-D-galactopyranoside(1400562-30-2)
• EPA Substance Registry System: phenyl 2,6-di-O-benzyl-3,4-di-O-chloroacetyl-1-thio-β-D-galactopyranoside(1400562-30-2)

Safety Data

• Hazardous Substances Data: 1400562-30-2(Hazardous Substances Data)

Upstream product

• 541-88-8 Chloroacetic anhydride 
• 258286-51-0 phenyl (6-O-benzyl-2-O-benzoyl-1-thio-β-D-galactopyranoside) 

Relevant articles and documents

An improved method for the synthesis of protected glycosyl fluorides from thioglycosides using N,N-diethylaminosulfur trifluoride (DAST)

The direct conversion of thioglycosides to glycosyl fluorides frequently used in oligosaccharide synthesis was examined using N,N-diethylaminosulfur trifluoride (DAST). Although the reaction proceeded without N-bromosuccinimide (NBS), in some cases it was found that the electrophilicity of the Vilsmeier-type electrophilic sulfinium cation species was not sufficient for the activation of certain less-reactive thioglycosides. Here, we report the results of fluorination reactions of a series of monosaccharides using DAST in the absence of NBS, and also discuss the acceleration of the reaction in the presence of dimethyl(methylthio)sulfonium trifluoromethanesulfonate (DMTST) resulting in excellent product yields.